what is Rosacea

Rosacea is a common chronic inflammatory disorder of the hair follicles, sebaceous glands and vasculature of the face. The role of Demodex mite in the pathogenesis of Rosacea is controversial. Rosacea sufferers have recurrent flushing, exacerbated by heat (shower, hot drinks), spicy foods, sunlight, cold, alcohol, and stress. They have sensitive skin, and may complain of dry and gritty eyes. The peak incidence of Rosacea is 30—50 yr; Females being more affected than Males. Rosacea sufferers may develop erythema, telangiectases, papules, and pustules of central face; there are no comedones in contrast to acne. Sebaceous hyperplasia, seborrheic dermatitis and facial lymphedema are also more common. There are 4 Major Subtypes of Rosacea: Erythematotelangiectatic, papulopustular, ocular, and phymatous. Chronic inflammation may progress to rhinophyma (enlarged nose; in males). Ocular involvement is also common (e.g., gritty, conjunctival injection, styes, photophobia). Investigations include clinical diagnosis; uncommonly, skin biopsy is indicated to rule out lupus or sarcoidosis. Similar conditions that needs to be differentiated from Rosacea are: Acne, lupus erythematosus, perioral dermatitis, sarcoidosis, seborrheic dermatitis. Treatment of Rosacea is based on severity and subtype. Lifestyle modification: Avoid triggers; sun protection and avoidance; facial massage for lymphedema. Topical antibiotics: Metronidazole 0.75% gel or 1% cream bid. Sodium sulfacetamide lotion 10% bid. Oral antibiotics (moderate to severe cases with inflammatory papulopustular component): Tetracycline 500 mg po bid Minocycline 100 mg po od—bid. Doxycycline 20 mg po bid (subantimicrobial dose therapy) or 100 mg po qd–bid. Isotretinoin (low dose); less commonly, topical retinoids may be used. Laser therapy (e.g., PDL, IPL) for telangiectases and ablative laser (e.g., CO2) for rhinophyma. Camouflage makeup (e.g., Dermablend, Covermark) for erythema. Ophthalmologist to assess for ocular Rosacea (blepharitis, conjunctivitis, episcleritis).

Wednesday, October 8, 2008

Acne Rosacea

Acne Rosacea is a chronic inflammatory skin condition of unknown cause. It occurs in persons whose skin is prone to flushing therefore it has been postulated that the underlying defect is vascular in nature. Acne Rosacea affects 1–10% of the population, it is more predominant in the middle aged and females.
Paler skin types, such as celts, northern European and the fair skinned are more prone to developing Acne Rosacea. It is characterised by the development of a red rash on the cheeks. The nose, forehead, scalp and eyes can become affected. The facial redness becomes persistent often with the presence of dilated blood vessels over cheeks. Acute attacks of papules,
pustules and edema can occur in response to various triggers. These attacks can persist for weeks.
Three distinct phases are recognised in the development of Acne Rosacea:
* phase 1
– Persistent facial redness
– Telangiectasia on cheeks, nose, forehead
– Sensitive, irritable skin
– Stinging and burning sensation on application of cosmetics and treatment creams
* phase 2
– Development of papules, pustules and lymphedema
– Skin follicles affected and sebaceous glands enlarged
– Prominent facial pores
– Extension of rash over face and scalp
* phase 3
– Persistent edematous, inflamed facial skin
– Facial contours become thickened, coarse and irregular
– Tissue overgrowth especially nose, chin, eyelids, ears and forehead
– Eye involvement with inflammation, irritation, redness, discomfort,
photosensitivity
– Inflamation of the cornea with disturbed vision
Triggers to acute flares
Certain substances and conditions are thought to trigger acute attacks of Acne Rosacea:
* Foods triggers
– Coffee, tea, chocolate, cold drinks, alcohol, soy sauce, cheese, citrus fruits,
curries, vinegar, tomatoes, red meat, yogurt
– Large meals
– Thermal heat
– Highly spiced foods, pickled foods, smoked foods, fermented foods
* Chemical triggers
– Caffeine, vasodilators, perfumes, aftershaves, astringents, cosmetics
* Environmental triggers
– Resident Demodex skin mite in follicles and sebaceous glands
– Gastrointestinal upset (e.g. diarrhoea, cholecystitis, gastritis)
– Weather conditions (e.g. Sunlight, wind)
– Heat and cold
* Other triggers
– Topical corticosteroids